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Identification of rate-limiting enzymes involved in paclitaxel biosynthesis pathway affected by coronatine and methyl-β-cyclodextrin in Taxus baccata L. cell suspension cultures
BACKGROUND: Paclitaxel is a potent antitumor alkaloid widely used for the treatment of several cancer types. This valuable secondary metabolite naturally exists in the inner bark of Taxus species in very low amounts. The small-scale production of paclitaxel in Taxus cell cultures requires utilizatio...
Autores principales: | Kashani, Kimia, Jalali Javaran, Mokhtar, Sabet, Mohammad Sadegh, Moieni, Ahmad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279667/ https://www.ncbi.nlm.nih.gov/pubmed/30377988 http://dx.doi.org/10.1007/s40199-018-0217-1 |
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