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Role of the Ebola membrane in the protection conferred by the three-mAb cocktail MIL77

MIL77, which has a higher manufacturing capacity than ZMapp, comprises MIL77-1, MIL77-2, and MIL77-3. The mechanisms by which these antibodies inhibit glycoprotein are unclear. Infection by viruses with lipid-bilayer envelopes occurs via the fusion of the viral membrane with the membrane of the targ...

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Detalles Bibliográficos
Autores principales: Cao, Ping, Bai, Haihong, Wang, Xinghe, Che, Jinjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279787/
https://www.ncbi.nlm.nih.gov/pubmed/30514891
http://dx.doi.org/10.1038/s41598-018-35964-6