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Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution

Regeneration of complex multi-tissue structures, such as limbs, requires the coordinated effort of multiple cell types. In axolotl limb regeneration, the wound epidermis and blastema have been extensively studied via histology, grafting, and bulk-tissue RNA-sequencing. However, defining the contribu...

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Detalles Bibliográficos
Autores principales: Leigh, Nicholas D., Dunlap, Garrett S., Johnson, Kimberly, Mariano, Rachelle, Oshiro, Rachel, Wong, Alan Y., Bryant, Donald M., Miller, Bess M., Ratner, Alex, Chen, Andy, Ye, William W., Haas, Brian J., Whited, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279788/
https://www.ncbi.nlm.nih.gov/pubmed/30514844
http://dx.doi.org/10.1038/s41467-018-07604-0