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The proton and metal binding sites responsible for the pH-dependent green-red bioluminescence color tuning in firefly luciferases

Firefly luciferases produce yellow-green light under physiological and alkaline conditions, however at acidic pH, higher temperatures or in the presence of heavy metals the color changes to red, a property called pH-sensitivity. Despite many decades of studies, the proton and metal binding sites res...

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Detalles Bibliográficos
Autores principales: Viviani, Vadim R., Gabriel, Gabriele V. M., Bevilaqua, Vanessa R., Simões, A. F., Hirano, T., Lopes-de-Oliveira, P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279810/
https://www.ncbi.nlm.nih.gov/pubmed/30514851
http://dx.doi.org/10.1038/s41598-018-33252-x