Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems

While cardiomyocytes differentiated from human induced pluripotent stems cells (hiPSCs) hold great promise for drug screening, the electrophysiological properties of these cells can be variable and immature, producing results that are significantly different from their human adult counterparts. Here...

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Detalles Bibliográficos
Autores principales: Tveito, Aslak, Jæger, Karoline Horgmo, Huebsch, Nathaniel, Charrez, Bérénice, Edwards, Andrew G., Wall, Samuel, Healy, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279833/
https://www.ncbi.nlm.nih.gov/pubmed/30514966
http://dx.doi.org/10.1038/s41598-018-35858-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279833/
https://www.ncbi.nlm.nih.gov/pubmed/30514966
http://dx.doi.org/10.1038/s41598-018-35858-7

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