Indoxyl Sulfate Promotes Arterial Thrombosis in Rat Model via Increased Levels of Complex TF/VII, PAI-1, Platelet Activation as Well as Decreased Contents of SIRT1 and SIRT3

Patients suffering from chronic kidney disease (CKD) are at a 20-fold higher risk of dying due to cardiovascular diseases (CVDs), primarily thrombosis following vascular injury. CKD is connected with retention of uremic toxins, especially indoxyl sulfate (IS), which are currently considered as a non...

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Detalles Bibliográficos
Autores principales: Karbowska, Malgorzata, Kaminski, Tomasz W., Znorko, Beata, Domaniewski, Tomasz, Misztal, Tomasz, Rusak, Tomasz, Pryczynicz, Anna, Guzinska-Ustymowicz, Katarzyna, Pawlak, Krystyna, Pawlak, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279869/
https://www.ncbi.nlm.nih.gov/pubmed/30546314
http://dx.doi.org/10.3389/fphys.2018.01623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279869/
https://www.ncbi.nlm.nih.gov/pubmed/30546314
http://dx.doi.org/10.3389/fphys.2018.01623

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