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Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

Neuronal signal transduction shapes brain function and malfunction may cause mental disorders. Despite the existence of functional genomics screens for proliferation and toxicity, neuronal signalling has been difficult to address so far. To overcome this limitation, we developed a pooled screening a...

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Detalles Bibliográficos
Autores principales: Herholt, Alexander, Brankatschk, Ben, Kannaiyan, Nirmal, Papiol, Sergi, Wichert, Sven P., Wehr, Michael C., Rossner, Moritz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279925/
https://www.ncbi.nlm.nih.gov/pubmed/30514868
http://dx.doi.org/10.1038/s41598-018-36008-9