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Perfluorophenyl Derivatives as Unsymmetrical Linkers for Solid Phase Conjugation

Linkers play major roles in conjugation chemistry toward the advancement of drug discovery. Two different series of fluorinated linkers were introduced to the backbone of a model peptide using solid phase peptide synthesis. These fluorinated linkers have the potential to conjugate two asymmetrical g...

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Detalles Bibliográficos
Autores principales: Alapour, Saba, Sharma, Anamika, de la Torre, Beatriz G., Ramjugernath, Deresh, Koorbanally, Neil A., Albericio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279949/
https://www.ncbi.nlm.nih.gov/pubmed/30547028
http://dx.doi.org/10.3389/fchem.2018.00589