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Proteasome lid bridges mitochondrial stress with Cdc53/Cullin1 NEDDylation status

Cycles of Cdc53/Cullin1 rubylation (a.k.a NEDDylation) protect ubiquitin-E3 SCF (Skp1-Cullin1-F-box protein) complexes from self-destruction and play an important role in mediating the ubiquitination of key protein substrates involved in cell cycle progression, development, and survival. Cul1 rubyla...

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Detalles Bibliográficos
Autores principales: Bramasole, L., Sinha, A., Gurevich, S., Radzinski, M., Klein, Y., Panat, N., Gefen, E., Rinaldi, T., Jimenez-Morales, D., Johnson, J., Krogan, N.J., Reis, N., Reichmann, D., Glickman, M.H., Pick, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279957/
https://www.ncbi.nlm.nih.gov/pubmed/30508698
http://dx.doi.org/10.1016/j.redox.2018.11.010