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Recruitment of Cytosolic J-Proteins by TOM Receptors Promotes Mitochondrial Protein Biogenesis

Mitochondria possess elaborate machineries for the import of proteins from the cytosol. Cytosolic factors like Hsp70 chaperones and their co-chaperones, the J-proteins, guide proteins to the mitochondrial surface. The translocase of the mitochondrial outer membrane (TOM) forms the entry gate for pre...

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Detalles Bibliográficos
Autores principales: Opaliński, Łukasz, Song, Jiyao, Priesnitz, Chantal, Wenz, Lena-Sophie, Oeljeklaus, Silke, Warscheid, Bettina, Pfanner, Nikolaus, Becker, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280124/
https://www.ncbi.nlm.nih.gov/pubmed/30463002
http://dx.doi.org/10.1016/j.celrep.2018.10.083