Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

BACKGROUND: Primary glioblastoma cell (GC) cultures have emerged as a key model in brain tumor research, with the potential to uncover patient-specific differences in therapy response. However, there is limited quantitative information about the stability of such cells during the initial 20–30 passa...

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Detalles Bibliográficos
Autores principales: Baskaran, Sathishkumar, Mayrhofer, Markus, Kultima, Hanna Göransson, Bergström, Tobias, Elfineh, Lioudmila, Cavelier, Lucia, Isaksson, Anders, Nelander, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280139/
https://www.ncbi.nlm.nih.gov/pubmed/29462414
http://dx.doi.org/10.1093/neuonc/noy024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280139/
https://www.ncbi.nlm.nih.gov/pubmed/29462414
http://dx.doi.org/10.1093/neuonc/noy024

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