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Revealing Unknown Protein Structures Using Computational Conformational Sampling Guided by Experimental Hydrogen-Exchange Data

Both experimental and computational methods are available to gather information about a protein’s conformational space and interpret changes in protein structure. However, experimentally observing and computationally modeling large proteins remain critical challenges for structural biology. Our work...

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Detalles Bibliográficos
Autores principales: Devaurs, Didier, Antunes, Dinler A., Kavraki, Lydia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280153/
https://www.ncbi.nlm.nih.gov/pubmed/30384411
http://dx.doi.org/10.3390/ijms19113406