β-Arrestin Based Receptor Signaling Paradigms: Potential Therapeutic Targets for Complex Age-Related Disorders

G protein coupled receptors (GPCRs) were first characterized as signal transducers that elicit downstream effects through modulation of guanine (G) nucleotide-binding proteins. The pharmacotherapeutic exploitation of this signaling paradigm has created a drug-based field covering nearly 50% of the c...

Descripción completa

Detalles Bibliográficos
Autores principales: van Gastel, Jaana, Hendrickx, Jhana O., Leysen, Hanne, Santos-Otte, Paula, Luttrell, Louis M., Martin, Bronwen, Maudsley, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280185/
https://www.ncbi.nlm.nih.gov/pubmed/30546309
http://dx.doi.org/10.3389/fphar.2018.01369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280185/
https://www.ncbi.nlm.nih.gov/pubmed/30546309
http://dx.doi.org/10.3389/fphar.2018.01369

Ejemplares similares