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Interleukin-4 Boosts Insulin-Induced Energy Deposits by Enhancing Glucose Uptake and Lipogenesis in Hepatocytes

Type 2 diabetes mellitus (T2DM), with dysregulated hepatic gluconeogenesis as the major cause of fasting hyperglycemia, is closely associated with chronic inflammation. We previously demonstrated interleukin-4 (IL-4) improves insulin sensitivity and glucose tolerance while reducing lipid deposits. T...

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Detalles Bibliográficos
Autores principales: Yang, Ching-Ping, Shiau, Ming-Yuh, Lai, Yi-Ren, Ho, Kuo-Ting, Hsiao, Chiao-Wan, Chen, Chun-Jung, Lo, Yu-Li, Chang, Yih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280305/
https://www.ncbi.nlm.nih.gov/pubmed/30584465
http://dx.doi.org/10.1155/2018/6923187