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FLT3 inhibitors in acute myeloid leukemia

FLT3 mutations are one of the most common findings in acute myeloid leukemia (AML). FLT3 inhibitors have been in active clinical development. Midostaurin as the first-in-class FLT3 inhibitor has been approved for treatment of patients with FLT3-mutated AML. In this review, we summarized the preclini...

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Detalles Bibliográficos
Autores principales: Wu, Mei, Li, Chuntuan, Zhu, Xiongpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280371/
https://www.ncbi.nlm.nih.gov/pubmed/30514344
http://dx.doi.org/10.1186/s13045-018-0675-4