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Validation of extracellular ligand–receptor interactions by Flow-TriCEPS

OBJECTIVE: The advent of ligand-based receptor capture methodologies, allows the identification of unknown receptor candidates for orphan extracellular ligands. However, further target validation can be tedious, laborious and time-consuming. Here, we present a methodology that provides a fast and co...

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Detalles Bibliográficos
Autores principales: Lopez-Garcia, Laura A., Demiray, Levent, Ruch-Marder, Sandra, Hopp, Ann-Katrin, Hottiger, Michael O., Helbling, Paul M., Pavlou, Maria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280402/
https://www.ncbi.nlm.nih.gov/pubmed/30518414
http://dx.doi.org/10.1186/s13104-018-3974-5