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A novel approach for rapid high-throughput selection of recombinant functional rat monoclonal antibodies

BACKGROUND: Most monoclonal antibodies against mouse antigens have been derived from rat spleen-mouse myeloma fusions, which are valuable tools for purposes ranging from general laboratory reagents to therapeutic drugs, and yet selecting and expressing them remains a time-consuming and inefficient p...

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Detalles Bibliográficos
Autores principales: Chen, Qin, Qiu, Shengping, Li, Huanhuan, Lin, Chaolong, Luo, Yong, Ren, Wenfeng, Zou, Yidi, Wang, Yale, Xia, Ninghshao, Huang, Chenghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280491/
https://www.ncbi.nlm.nih.gov/pubmed/30514214
http://dx.doi.org/10.1186/s12865-018-0274-8