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A novel approach for rapid high-throughput selection of recombinant functional rat monoclonal antibodies
BACKGROUND: Most monoclonal antibodies against mouse antigens have been derived from rat spleen-mouse myeloma fusions, which are valuable tools for purposes ranging from general laboratory reagents to therapeutic drugs, and yet selecting and expressing them remains a time-consuming and inefficient p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280491/ https://www.ncbi.nlm.nih.gov/pubmed/30514214 http://dx.doi.org/10.1186/s12865-018-0274-8 |