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Lasso regularization for left-censored Gaussian outcome and high-dimensional predictors

BACKGROUND: Biological assays for the quantification of markers may suffer from a lack of sensitivity and thus from an analytical detection limit. This is the case of human immunodeficiency virus (HIV) viral load. Below this threshold the exact value is unknown and values are consequently left-censo...

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Detalles Bibliográficos
Autores principales: Soret, Perrine, Avalos, Marta, Wittkop, Linda, Commenges, Daniel, Thiébaut, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280495/
https://www.ncbi.nlm.nih.gov/pubmed/30514234
http://dx.doi.org/10.1186/s12874-018-0609-4