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Recombinant Adenovirus KGHV500 and CIK Cells Codeliver Anti-p21-Ras scFv for the Treatment of Gastric Cancer with Wild-Type Ras Overexpression

The development of gastric cancer is frequently related to the overexpression of wild-type p21 proteins, but it is rarely related to mutated Ras proteins. We previously constructed a broad-spectrum anti-p21-Ras single-chain variable fragment antibody (scFv), which was carried by the oncolytic adenov...

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Detalles Bibliográficos
Autores principales: Wang, Mingjuan, Hong, Yanling, Feng, Qiang, Pan, Xinyan, Song, Shuling, Cui, Jing, Lei, Jin, Fang, Hong, Yang, Julun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280635/
https://www.ncbi.nlm.nih.gov/pubmed/30534583
http://dx.doi.org/10.1016/j.omto.2018.10.003