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Discordance between FISH, IHC, and NGS Analysis of ALK Status in Advanced Non–Small Cell Lung Cancer (NSCLC): a Brief Report of 7 Cases()

BACKGROUND: Anaplastic lymphoma kinase (ALK) rearrangement represents a landmark in the targeted therapy of non–small cell lung cancer (NSCLC). Immunohistochemistry (IHC) is a sensitive and specific method to detect ALK protein expression, possibly an alternative to fluorescence in situ hybridizatio...

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Detalles Bibliográficos
Autores principales: Scattone, Anna, Catino, Annamaria, Schirosi, Laura, Caldarola, Lucia, Tommasi, Stefania, Lacalamita, Rosanna, Montagna, Elisabetta Sara, Galetta, Domenico, Serio, Gabriella, Zito, Francesco Alfredo, Mangia, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280637/
https://www.ncbi.nlm.nih.gov/pubmed/30529852
http://dx.doi.org/10.1016/j.tranon.2018.11.006