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IFN-β Plays Both Pro- and Anti-inflammatory Roles in the Rat Cardiac Fibroblast Through Differential STAT Protein Activation

Cardiac fibroblasts (CFs) contribute to theinflammatory response to tissue damage, secreting both pro- and anti-inflammatory cytokines and chemokines. Interferon beta (IFN-β) induces the phosphorylation of signal transducer and activator of transcription (STAT) proteins through the activation of its...

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Detalles Bibliográficos
Autores principales: Bolívar, Samir, Anfossi, Renatto, Humeres, Claudio, Vivar, Raúl, Boza, Pía, Muñoz, Claudia, Pardo-Jimenez, Viviana, Olivares-Silva, Francisco, Díaz-Araya, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280699/
https://www.ncbi.nlm.nih.gov/pubmed/30555324
http://dx.doi.org/10.3389/fphar.2018.01368