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Expanding heterochromatin reveals discrete subtelomeric domains delimited by chromatin landscape transitions

The eukaryotic genome is divided into chromosomal domains of heterochromatin and euchromatin. Transcriptionally silent heterochromatin is found at subtelomeric regions, leading to the telomeric position effect (TPE) in yeast, fly, and human. Heterochromatin generally initiates and spreads from defin...

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Detalles Bibliográficos
Autores principales: Hocher, Antoine, Ruault, Myriam, Kaferle, Petra, Descrimes, Marc, Garnier, Mickaël, Morillon, Antonin, Taddei, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280759/
https://www.ncbi.nlm.nih.gov/pubmed/30355601
http://dx.doi.org/10.1101/gr.236554.118