Pharmaceutical and pharmacokinetic evaluation of novel rectal mucoadhesive hydrogels containing tolmetin sodium

The objective of the present study was to develop rectal mucoadhesive hydrogels loaded with Tolmetin Sodium, a non-steroidal anti-inflammatory drug, for prolonged duration of action and increased bioavailability. Fourteen formulae were prepared with different types and concentrations of polymers as...

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Detalles Bibliográficos
Autores principales: Ramadan, Afaf A., Elbakry, Asmaa M., Esmaeil, Asmaa H., Khaleel, Sahar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280843/
https://www.ncbi.nlm.nih.gov/pubmed/30595939
http://dx.doi.org/10.1007/s40005-017-0365-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280843/
https://www.ncbi.nlm.nih.gov/pubmed/30595939
http://dx.doi.org/10.1007/s40005-017-0365-1

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