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Pharmaceutical and pharmacokinetic evaluation of novel rectal mucoadhesive hydrogels containing tolmetin sodium
The objective of the present study was to develop rectal mucoadhesive hydrogels loaded with Tolmetin Sodium, a non-steroidal anti-inflammatory drug, for prolonged duration of action and increased bioavailability. Fourteen formulae were prepared with different types and concentrations of polymers as...
Autores principales: | Ramadan, Afaf A., Elbakry, Asmaa M., Esmaeil, Asmaa H., Khaleel, Sahar A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280843/ https://www.ncbi.nlm.nih.gov/pubmed/30595939 http://dx.doi.org/10.1007/s40005-017-0365-1 |
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