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Intercalated theophylline-smectite hybrid for pH-mediated delivery

On the basis of their large specific surface areas, high adsorption and cation exchange capacities, swelling potential and low toxicity, natural smectite clays are attractive substrates for the gastric protection of neutral and cationic drugs. Theophylline is an amphoteric xanthine derivative that i...

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Detalles Bibliográficos
Autores principales: Trivedi, Vivek, Nandi, Uttom, Maniruzzaman, Mohammed, Coleman, Nichola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280968/
https://www.ncbi.nlm.nih.gov/pubmed/29363036
http://dx.doi.org/10.1007/s13346-018-0478-8