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Intercalated theophylline-smectite hybrid for pH-mediated delivery
On the basis of their large specific surface areas, high adsorption and cation exchange capacities, swelling potential and low toxicity, natural smectite clays are attractive substrates for the gastric protection of neutral and cationic drugs. Theophylline is an amphoteric xanthine derivative that i...
Autores principales: | Trivedi, Vivek, Nandi, Uttom, Maniruzzaman, Mohammed, Coleman, Nichola J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280968/ https://www.ncbi.nlm.nih.gov/pubmed/29363036 http://dx.doi.org/10.1007/s13346-018-0478-8 |
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