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The conservation landscape of the human ribosomal RNA gene repeats

Ribosomal RNA gene repeats (rDNA) encode ribosomal RNA, a major component of ribosomes. Ribosome biogenesis is central to cellular metabolic regulation, and several diseases are associated with rDNA dysfunction, notably cancer, However, its highly repetitive nature has severely limited characterizat...

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Detalles Bibliográficos
Autores principales: Agrawal, Saumya, Ganley, Austen R. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281188/
https://www.ncbi.nlm.nih.gov/pubmed/30517151
http://dx.doi.org/10.1371/journal.pone.0207531