Trypanosoma cruzi-specific IFN-γ-producing cells in chronic Chagas disease associate with a functional IL-7/IL-7R axis

BACKGROUND: The severity of cardiac disease in chronic Chagas disease patients is associated with different features of T-cell exhaustion. Here, we assessed whether the ability of T cells to secrete IFN-γ in response to T. cruzi was linked to disruption in immune homeostasis and inflammation in pati...

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Detalles Bibliográficos
Autores principales: Natale, María A., César, Gonzalo A., Alvarez, María G., Castro Eiro, Melisa D., Lococo, Bruno, Bertocchi, Graciela, Albareda, María C., Laucella, Susana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281225/
https://www.ncbi.nlm.nih.gov/pubmed/30517089
http://dx.doi.org/10.1371/journal.pntd.0006998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281225/
https://www.ncbi.nlm.nih.gov/pubmed/30517089
http://dx.doi.org/10.1371/journal.pntd.0006998

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