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Exploiting antigen receptor information to quantify index switching in single-cell transcriptome sequencing experiments
By offering high sequencing speed and ultra-high-throughput at a low price, Illumina next-generation sequencing platforms have been widely adopted in recent years. However, an experiment with multiplexed library could be at risk of molecular recombination, known as “index switching”, which causes a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281226/ https://www.ncbi.nlm.nih.gov/pubmed/30517183 http://dx.doi.org/10.1371/journal.pone.0208484 |