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Engineering Cell Surfaces by Covalent Grafting of Synthetic Polymers to Metabolically-Labeled Glycans

[Image: see text] Re-engineering mammalian cell surfaces enables modulation of their phenotype, function, and interactions with external markers and may find application in cell-based therapies. Here we use metabolic glycan labeling to install azido groups onto the cell surface, which can act as anc...

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Detalles Bibliográficos
Autores principales: Tomás, Ruben M. F., Martyn, Benjamin, Bailey, Trisha L., Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281312/
https://www.ncbi.nlm.nih.gov/pubmed/30533278
http://dx.doi.org/10.1021/acsmacrolett.8b00675