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TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro

Amyloid-β peptide (Aβ) forms plaques in Alzheimer’s disease (AD) and is responsible for early cognitive deficits in AD patients. Advancing cognitive decline is accompanied by progressive impairment of cognition-relevant EEG patterns such as gamma oscillations. The endocannabinoid anandamide, a TrpV1...

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Detalles Bibliográficos
Autores principales: Balleza-Tapia, Hugo, Crux, Sophie, Andrade-Talavera, Yuniesky, Dolz-Gaiton, Pablo, Papadia, Daniela, Chen, Gefei, Johansson, Jan, Fisahn, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281315/
https://www.ncbi.nlm.nih.gov/pubmed/30417826
http://dx.doi.org/10.7554/eLife.37703