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Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD(+) in axon regeneration

The mechanisms underlying axon regeneration in mature neurons are relevant to the understanding of normal nervous system maintenance and for developing therapeutic strategies for injury. Here, we report novel pathways in axon regeneration, identified by extending our previous function-based screen u...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Won, Tang, Ngang Heok, Piggott, Christopher A, Andrusiak, Matthew G, Park, Seungmee, Zhu, Ming, Kurup, Naina, Cherra, Salvatore J, Wu, Zilu, Chisholm, Andrew D, Jin, Yishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281318/
https://www.ncbi.nlm.nih.gov/pubmed/30461420
http://dx.doi.org/10.7554/eLife.39756