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Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury

Renal ischemia/reperfusion (I/R) injury occurs in patients undergoing renal transplantation and with acute kidney injury and is responsible for the development of chronic allograft dysfunction as characterized by parenchymal alteration and fibrosis. Heparanase (HPSE), an endoglycosidase that regulat...

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Detalles Bibliográficos
Autores principales: Masola, Valentina, Bellin, Gloria, Vischini, Gisella, Dall'Olmo, Luigi, Granata, Simona, Gambaro, Giovanni, Lupo, Antonio, Onisto, Maurizio, Zaza, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281411/
https://www.ncbi.nlm.nih.gov/pubmed/30546836
http://dx.doi.org/10.18632/oncotarget.26324