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Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury
Renal ischemia/reperfusion (I/R) injury occurs in patients undergoing renal transplantation and with acute kidney injury and is responsible for the development of chronic allograft dysfunction as characterized by parenchymal alteration and fibrosis. Heparanase (HPSE), an endoglycosidase that regulat...
Autores principales: | Masola, Valentina, Bellin, Gloria, Vischini, Gisella, Dall'Olmo, Luigi, Granata, Simona, Gambaro, Giovanni, Lupo, Antonio, Onisto, Maurizio, Zaza, Gianluigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281411/ https://www.ncbi.nlm.nih.gov/pubmed/30546836 http://dx.doi.org/10.18632/oncotarget.26324 |
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