Identification of rare levels of methylated tumor DNA fragments using an optimized bias based pre-amplification-digital droplet PCR (OBBPA-ddPCR)

BACKGROUND: The analysis of aberrant DNA methylations is used for the diagnosis of cancer as significant changes in the gene methylation pattern are often detected during early carcinogenesis. In this study, we evaluated the performance of a two-step method that combines pre-amplification with ddPCR...

Descripción completa

Detalles Bibliográficos
Autores principales: Menschikowski, Mario, Jandeck, Carsten, Friedemann, Markus, Nacke, Brit, Hantsche, Saskia, Tiebel, Oliver, Sukocheva, Olga, Hagelgans, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281424/
https://www.ncbi.nlm.nih.gov/pubmed/30546833
http://dx.doi.org/10.18632/oncotarget.26315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281424/
https://www.ncbi.nlm.nih.gov/pubmed/30546833
http://dx.doi.org/10.18632/oncotarget.26315

Ejemplares similares