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emClarity: Software for High Resolution Cryo-electron Tomography and Sub-tomogram Averaging
Macromolecular complexes are intrinsically flexible and often challenging to purify for structure determination by single particle cryoEM. Such complexes may be studied using cryo-electron tomography combined with sub-tomogram alignment and classification, which in exceptional cases reaches sub-nano...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281437/ https://www.ncbi.nlm.nih.gov/pubmed/30349041 http://dx.doi.org/10.1038/s41592-018-0167-z |