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The spatial distribution pattern of Connexin26 expression in supporting cells and its role in outer hair cell survival

Mutations in the GJB2 gene (which encodes Connexin26 (Cx26)) account for about a quarter of all cases of non-syndromic deafness. Previous studies have indicated that knockout (KO) of Gjb2 gene during early postnatal days can cause outer hair cell (OHC) loss in mouse models. However, the postnatal sp...

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Detalles Bibliográficos
Autores principales: Chen, Sen, Xu, Kai, Xie, Le, Cao, Hai-Yan, Wu, Xia, Du, An-Na, He, Zu-Hong, Lin, Xi, Sun, Yu, Kong, Wei-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281596/
https://www.ncbi.nlm.nih.gov/pubmed/30518746
http://dx.doi.org/10.1038/s41419-018-1238-x