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Enrichment of the fetal fraction in non-invasive prenatal screening reduces maternal background interference

Measurement of cell-free fetal DNA (cffDNA) is an indispensable process for non-invasive prenatal screening (NIPS). According to recent studies, cffDNA in maternal plasma can be enriched for various lengths of fragments, and a sufficient amount of cffDNA can effectively eliminate background interfer...

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Detalles Bibliográficos
Autores principales: Liang, Bo, Li, Hong, He, Quanze, Li, Haibo, Kong, Lingyin, Xuan, Liming, Xia, Yingying, Shen, Jingjing, Mao, Yan, Li, Yixue, Wang, Ting, Zhao, Yi-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281613/
https://www.ncbi.nlm.nih.gov/pubmed/30518878
http://dx.doi.org/10.1038/s41598-018-35738-0