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A semi-supervised approach for predicting cell-type specific functional consequences of non-coding variation using MPRAs

Predicting the functional consequences of genetic variants in non-coding regions is a challenging problem. We propose here a semi-supervised approach, GenoNet, to jointly utilize experimentally confirmed regulatory variants (labeled variants), millions of unlabeled variants genome-wide, and more tha...

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Detalles Bibliográficos
Autores principales:	He, Zihuai, Liu, Linxi, Wang, Kai, Ionita-Laza, Iuliana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281617/ https://www.ncbi.nlm.nih.gov/pubmed/30518757 http://dx.doi.org/10.1038/s41467-018-07349-w

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