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Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity

Angiogenesis is crucial for tissue development and homeostasis; however, excessive angiogenesis can lead to diseases, including arthritis and cancer metastasis. Some antiangiogenic drugs are available, but side effects remain problematic. Thus, alternative angiogenesis inhibition strategies are need...

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Detalles Bibliográficos
Autores principales: Ikeuchi, Tomoko, de Vega, Susana, Forcinito, Patricia, Doyle, Andrew D., Amaral, Juan, Rodriguez, Ignacio R., Arikawa-Hirasawa, Eri, Yamada, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281620/
https://www.ncbi.nlm.nih.gov/pubmed/30518776
http://dx.doi.org/10.1038/s41598-018-36182-w