Tracking plasma DNA mutation dynamics in estrogen receptor positive metastatic breast cancer with dPCR-SEQ

Serial monitoring of plasma DNA mutations in estrogen receptor positive metastatic breast cancer (ER + MBC) holds promise as an early predictor of therapeutic response. Here, we developed dPCR-SEQ, a customized assay that utilizes digital PCR-based target enrichment followed by next-generation seque...

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Detalles Bibliográficos
Autores principales: Kumar, Sunil, Lindsay, Daniel, Chen, Q. Brent, Garrett, Amy L., Tan, Xianming M., Anders, Carey K., Carey, Lisa A., Gupta, Gaorav P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281679/
https://www.ncbi.nlm.nih.gov/pubmed/30534596
http://dx.doi.org/10.1038/s41523-018-0093-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281679/
https://www.ncbi.nlm.nih.gov/pubmed/30534596
http://dx.doi.org/10.1038/s41523-018-0093-3

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