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GLIS3 and Thyroid: A Pleiotropic Candidate Gene for Congenital Hypothyroidism
Variations in the transcription factor Gli-similar 3 (GLIS3) gene have been associated to variable congenital endocrine defects, including both morphogenetic and functional thyroid alterations. Evidence from Glis3 knockout mice indicates a relevant role for GLIS3 in thyroid hormone biosynthesis and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281699/ https://www.ncbi.nlm.nih.gov/pubmed/30555422 http://dx.doi.org/10.3389/fendo.2018.00730 |