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GLIS3 and Thyroid: A Pleiotropic Candidate Gene for Congenital Hypothyroidism

Variations in the transcription factor Gli-similar 3 (GLIS3) gene have been associated to variable congenital endocrine defects, including both morphogenetic and functional thyroid alterations. Evidence from Glis3 knockout mice indicates a relevant role for GLIS3 in thyroid hormone biosynthesis and...

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Detalles Bibliográficos
Autores principales: Rurale, Giuditta, Persani, Luca, Marelli, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281699/
https://www.ncbi.nlm.nih.gov/pubmed/30555422
http://dx.doi.org/10.3389/fendo.2018.00730