Human CD8(+)HLA-DR(+) Regulatory T Cells, Similarly to Classical CD4(+)Foxp3(+) Cells, Suppress Immune Responses via PD-1/PD-L1 Axis

We have previously identified a human CD8(+)HLA-DR(+) regulatory T cell subset with the ability to suppress proliferation of autologous PBMCs responder cells through cell contact and CTLA-4 co-inhibitory molecule. The present study characterizes the complete phenotype of CD8(+)HLA-DR(+) Treg cells w...

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Detalles Bibliográficos
Autores principales: Machicote, Andres, Belén, Santiago, Baz, Placida, Billordo, Luis A., Fainboim, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281883/
https://www.ncbi.nlm.nih.gov/pubmed/30555473
http://dx.doi.org/10.3389/fimmu.2018.02788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281883/
https://www.ncbi.nlm.nih.gov/pubmed/30555473
http://dx.doi.org/10.3389/fimmu.2018.02788

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