Arginase-1 Is Responsible for IL-13-Mediated Susceptibility to Trypanosoma cruzi Infection

Arginase-1 (Arg-1) is a marker for alternatively activated macrophages (AAM) and is mainly induced by the type 2 cytokines interleukin (IL)-4 and IL-13 through the common IL-4 receptor-alpha (Rα) subunit. Both, Arg-1 and AAM undermine macrophage effector functions against intracellular parasites and...

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Detalles Bibliográficos
Autores principales: Abad Dar, Mahin, Hölscher, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281981/
https://www.ncbi.nlm.nih.gov/pubmed/30555475
http://dx.doi.org/10.3389/fimmu.2018.02790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281981/
https://www.ncbi.nlm.nih.gov/pubmed/30555475
http://dx.doi.org/10.3389/fimmu.2018.02790

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