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Extended Freeze-Dried BCG Instructed pDCs Induce Suppressive Tregs and Dampen EAE

Several clinical observations have shown that Bacillus Calmette-Guérin (BCG) vaccine has beneficial impact on patients suffering from different chronic inflammatory diseases. Here we evaluated whether BCG inactivated by Extended Freeze-Drying (EFD) which circumvents all the side effects linked to th...

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Detalles Bibliográficos
Autores principales: Lippens, Carla, Garnier, Laure, Guyonvarc'h, Pierre-Marie, Santiago-Raber, Marie-Laure, Hugues, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281986/
https://www.ncbi.nlm.nih.gov/pubmed/30555468
http://dx.doi.org/10.3389/fimmu.2018.02777