Cargando…

Extended Freeze-Dried BCG Instructed pDCs Induce Suppressive Tregs and Dampen EAE

Several clinical observations have shown that Bacillus Calmette-Guérin (BCG) vaccine has beneficial impact on patients suffering from different chronic inflammatory diseases. Here we evaluated whether BCG inactivated by Extended Freeze-Drying (EFD) which circumvents all the side effects linked to th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lippens, Carla, Garnier, Laure, Guyonvarc'h, Pierre-Marie, Santiago-Raber, Marie-Laure, Hugues, Stéphanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281986/ https://www.ncbi.nlm.nih.gov/pubmed/30555468 http://dx.doi.org/10.3389/fimmu.2018.02777

Ejemplares similares

IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity
por: Lippens, Carla, et al.
Publicado: (2016)

Innate sensing of viral infection by pDCs and regulation by IFN-α and HMGB1 of TRAIL expression on pDCs and NK cells
por: Saïdi, Héla, et al.
Publicado: (2014)

Physical Exercise Induces Immunoregulation of TREG, M2, and pDCs in a Lung Allergic Inflammation Model
por: Fernandes, Paula, et al.
Publicado: (2019)

NK-pDC cross-talk leads to the generation of mTRAIL+IFN-α+cytotoxic pDCs following HIV-1 infection of pDCs. Consequences on the control of viral replication
por: Saïdi, Héla, et al.
Publicado: (2010)

Phenotypic and functional alterations of pDCs in lupus-prone mice
por: Zhou, Zhenyuan, et al.
Publicado: (2016)

Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses
por: Chaudhary, Vidyanath, et al.
Publicado: (2022)

New role for antigen-presenting activated pDCs in promoting Th17 cells and impacting antitumor immunity
por: Guéry, Leslie, et al.
Publicado: (2015)

Compare mDCs and pDCs between two distinct patients groups in acute HIV-1 infection
por: Jiao, Yanmei, et al.
Publicado: (2014)

Data on PRRSV infection promoted the subtype of porcine dendritic cells from mDCs to pDCs in vivo
por: Liu, Jinling, et al.
Publicado: (2016)

Relationships between IL-17(+) Subsets, Tregs and pDCs That Distinguish among SIV Infected Elite Controllers, Low, Medium and High Viral Load Rhesus Macaques
por: Khowawisetsut, Ladawan, et al.
Publicado: (2013)

Emergence of IFN-alpha TRAIL-expressing killer pDCs (IKpDCs) as a consequence of a crosstalk with NK cells. Influence of HIV-1 infection and implication of HMGB1
por: Bras, Marlène, et al.
Publicado: (2012)

Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN
por: Shimizu, Kanako, et al.
Publicado: (2019)

The Role of Interleukin 18/Interleukin 18-Binding Protein in Adult-Onset Still’s Disease and Systemic Juvenile Idiopathic Arthritis
por: Girard-Guyonvarc’h, Charlotte, et al.
Publicado: (2022)

Lack of Association Between Sex Hormones, MDSCs, LDGs and pDCs in Males and Females With Systemic Lupus Erythematosus
por: Jones, Jessica M., et al.
Publicado: (2022)

Plasmacytoid Dendritic cells (pDCs) in HIV-infected and HIV/HCV-co-infected patients receiving successful treatment
por: Khokhlova, Olga, et al.
Publicado: (2014)

CSL362 potently and specifically depletes pDCs invitro and ablates SLE-immune complex-induced IFN responses
por: Monaghan, Katherine A., et al.
Publicado: (2023)

Neonatal Plasmacytoid Dendritic Cells (pDCs) Display Subset Variation but Can Elicit Potent Anti-Viral Innate Responses
por: Zhang, Xiaoming, et al.
Publicado: (2013)

Hepatitis B virus exploits C‐type lectin receptors to hijack cDC1s, cDC2s and pDCs
por: Ouaguia, Laurissa, et al.
Publicado: (2020)

Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs
por: Ma, Shixin, et al.
Publicado: (2017)

Demonstrating Functional Equivalence of Pilot and Production Scale Freeze-Drying of BCG
por: ten Have, R., et al.
Publicado: (2016)

Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—A new target for lupus treatment
por: Smith, Nikaïa, et al.
Publicado: (2019)

Mesenchymal Stem Cells Alleviate Moderate-to-Severe Psoriasis by Reducing the Production of Type I Interferon (IFN-I) by Plasmacytoid Dendritic Cells (pDCs)
por: Chen, Maosheng, et al.
Publicado: (2019)

Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19
por: Laurent, Paôline, et al.
Publicado: (2022)

CD226 Attenuates Treg Proliferation via Akt and Erk Signaling in an EAE Model
por: Wang, Ning, et al.
Publicado: (2020)

Mutation in Irf8 Gene (Irf8(R294C) ) Impairs Type I IFN-Mediated Antiviral Immune Response by Murine pDCs
por: Das, Annesa, et al.
Publicado: (2021)

Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS
por: Koutrolos, Michail, et al.
Publicado: (2014)

Sedimentation and mobility of PDCs: a reappraisal of ignimbrites’ aspect ratio
por: Giordano, Guido, et al.
Publicado: (2017)

Interleukin-15 enhances proinflammatory T-cell responses in patients with MS and EAE
por: Laurent, Cyril, et al.
Publicado: (2020)

pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation
por: Duraes, Fernanda V., et al.
Publicado: (2016)

The role of interleukin-18 and interleukin-18 binding protein in K/BxN serum transfer-induced arthritis
por: Fauteux-Daniel, Sebastien, et al.
Publicado: (2023)

BDCA1(+) cDC2s, BDCA2(+) pDCs and BDCA3(+) cDC1s reveal distinct pathophysiologic features and impact on clinical outcomes in melanoma patients
por: Sosa Cuevas, Eleonora, et al.
Publicado: (2020)

IL-10 Dampens the Th1 and Tc Activation through Modulating DC Functions in BCG Vaccination
por: Xu, Hui, et al.
Publicado: (2019)

Pure & crystallized 2D Boron Nitride sheets synthesized via a novel process coupling both PDCs and SPS methods
por: Yuan, Sheng, et al.
Publicado: (2016)

Membrane-Bound TNF Induces Protective Immune Responses to M. bovis BCG Infection: Regulation of memTNF and TNF Receptors Comparing Two memTNF Molecules
por: Olleros, Maria L., et al.
Publicado: (2012)

Exosomes with FOXP3 from gene-modified dendritic cells ameliorate the development of EAE by regulating the balance of Th/Treg
por: Jia, Zhen, et al.
Publicado: (2022)

The Resistance to Freeze-Drying and to Storage Was Determined as the Cellular Ability to Recover Its Survival Rate and Acidification Activity
por: Coulibaly, Ibourahema, et al.
Publicado: (2010)

Cannabinoids induce functional Tregs by promoting tolerogenic DCs via autophagy and metabolic reprograming
por: Angelina, Alba, et al.
Publicado: (2021)

Ash clouds temperature estimation. Implication on dilute and concentrated PDCs coupling and topography confinement
por: Pensa, A., et al.
Publicado: (2019)

Applications of the European Parkinson’s Disease Association sponsored Parkinson’s Disease Composite Scale (PDCS)
por: Balestrino, Roberta, et al.
Publicado: (2019)

Dysfunctional BTN3A together with deregulated immune checkpoints and type I/II IFN dictate defective interplay between pDCs and γδ T cells in melanoma patients, which impacts clinical outcomes
por: Girard, Pauline, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dui2geag64j1dq1bf7jhdtei9t