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The HDAC6 Inhibitor Trichostatin A Acetylates Microtubules and Protects Axons From Excitotoxin-Induced Degeneration in a Compartmented Culture Model

Axon degeneration has been implicated as a pathological process in several neurodegenerative diseases and acquired forms of neural injury. We have previously shown that stabilizing microtubules can protect axons against excitotoxin-induced fragmentation, however, the alterations of microtubules foll...

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Detalles Bibliográficos
Autores principales: Hanson, Kelsey, Tian, Nan, Vickers, James C., King, Anna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282003/
https://www.ncbi.nlm.nih.gov/pubmed/30555293
http://dx.doi.org/10.3389/fnins.2018.00872