A humanized yeast-based toolkit for monitoring phosphatidylinositol 3-kinase activity at both single cell and population levels

Phosphatidylinositol 3-kinase (PI3K) is a key regulator of phosphoinositide-dependent signaling in mammalian cells and its dysfunction is related to multiple syndromes, including cancer. By heterologous expression in Saccharomyces cerevisiae, we have developed a humanized yeast system as a tool for...

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Detalles Bibliográficos
Autores principales: Coronas-Serna, Julia María, Fernández-Acero, Teresa, Molina, María, Cid, Víctor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282018/
https://www.ncbi.nlm.nih.gov/pubmed/30533419
http://dx.doi.org/10.15698/mic2018.12.660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282018/
https://www.ncbi.nlm.nih.gov/pubmed/30533419
http://dx.doi.org/10.15698/mic2018.12.660

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