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A humanized yeast-based toolkit for monitoring phosphatidylinositol 3-kinase activity at both single cell and population levels
Phosphatidylinositol 3-kinase (PI3K) is a key regulator of phosphoinositide-dependent signaling in mammalian cells and its dysfunction is related to multiple syndromes, including cancer. By heterologous expression in Saccharomyces cerevisiae, we have developed a humanized yeast system as a tool for...
Autores principales: | Coronas-Serna, Julia María, Fernández-Acero, Teresa, Molina, María, Cid, Víctor J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282018/ https://www.ncbi.nlm.nih.gov/pubmed/30533419 http://dx.doi.org/10.15698/mic2018.12.660 |
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