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TRH Analog, Taltirelin Improves Motor Function of Hemi-PD Rats Without Inducing Dyskinesia via Sustained Dopamine Stimulating Effect

Thyrotropin-releasing hormone (TRH) and its analogs are able to stimulate the release of the endogenic dopamine (DA) in the central nervous system. However, this effect has not been tested in the Parkinson’s disease (PD), which is characterized by the DA deficiency due to the dopaminergic neurons lo...

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Detalles Bibliográficos
Autores principales: Zheng, Cong, Chen, Guiqin, Tan, Yang, Zeng, Weiqi, Peng, Qiwei, Wang, Ji, Cheng, Chi, Yang, Xiaoman, Nie, Shuke, Xu, Yan, Zhang, Zhentao, Papa, Stella M., Ye, Keqiang, Cao, Xuebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282053/
https://www.ncbi.nlm.nih.gov/pubmed/30555300
http://dx.doi.org/10.3389/fncel.2018.00417